| Clone | 2D2 |
| Isotype | IgG1 |
| Product Type | Monoclonal Antibody |
| Units | 100 µg |
| Host | Mouse |
| Species reactivity | Human |
| Application | Western Blotting |
BackgroundThe immunogen for the anti-h bax was a synthetic peptide corresponding to amino acids 3 to 16 of the human bax sequence.Bax expression is associated with cell death regulation. The ratio of bax to other bcl-2 family members is believed to regulate apoptosis.
Synonyms: hbax, mouse anti human bax
Source
Immunogen: A synthetic peptide corresponding to amino acids 3 to 16 of the human bax sequence
Product
Product Form: Unconjugated
Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide
Purification Method: Protein A/G Chromatography
Concentration: See vial for concentration
ApplicationsApplications: Western Blot 1:10,000
Functional Analysis: Western Blotting
StorageProduct should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles
Product Stability: Products are stable for one year from purchase when stored properly
Shipping Conditions: Ship at ambient temperature, freeze upon arrival
CautionThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
References1. Y.T.Hsu et. al. (1997) J. Biol. Chem.,272(21): 13829-138342. Y. T. Hsu et. al (1997) Proc. Natl. Acad. Sci. USA, 94:3668-3672 3. Annis, M., et al, 'Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis' EMBO Journal 2005, 24, , 2096-21034. Soucie, E.L., et al, 'Myc Potentiates Apoptosis by Stimulating Bax Activity at the Mitochondria' Molecular and Cell Biology 2001, 21, , 4725-4736
Protein Reference(s)
Database Name: UniProt
Accession number: Q07812 - Bax-alpha Q07814 - Bax-beta
Safety Datasheet(s) for this product:NM_Sodium Azide/wp-content/uploads/SDS/Antibody SDS with Sodium Azide Noridic-MUbio.pdf
