Background:

Naproxenisananti-inflammatorydrugusedforpainrelief,feverreductionandagainstswelling.Apparently,italsohassomeanti-viralactivity.Itbelongstothemostsoldover-the-counterdrugs.Itisfoundintheenvironment,especiallyinthewaterenvironmentintheneighbourhoodoflargecitiesandhospitals.

Source:

Rabbitimmuneserum

Product:

Eachvialcontains0.1ml10mg/mlpurifiedIgG

Applications:

Dilutionof1/2,000fromthedeliveredimmuneserum.(Thetiterisdefinedasthedilutionthatgives50%oftheabsorbancefromthemaximumabsorbancewhentestedwithELISA).SuggestedconcentrationtouseinELISA:1/2,000fromthedeliveredsolution.Platesarecoatedwith400ng/mlOVA-derivative.HRP-conjugatedanti-rabbitIgGasatracer1/8,000ImmunogenBSA-Derivativeconjugate

CrossReactivity:

Compoundtested%Cross-reactivityBezafibrate5%Gemfibrozil8%BisphenolA5%Ibuprofen9%Clofibrinicacid5%Metoprolol6%Diclofenac4%Naproxen100%Erythromycine3%Octylphenol10%Fenofibrate6%Propanolol6%

Specificity:

Immunogen:BSA-Naproxenderivativeconjugate,Target:Naproxen,CASno.:22204-5-1,Solubility:Organicsolvents,PEGs.

Storage:

Storeat4°Coraliquotandstoreat-20°Cforlongerperiods.Precautionsshouldbetakenuponstorageforlongerperiods.ProblemsoflongtermstABIlitymayoccurwithhighlydilutedsolutions.Nootherpreservativeagenthasbeenaddedtothepresentformulation.Forlongstoragepurposesinsolutiontheadditionofsodiumazideat0.02%isadvisedwiththeappropriateprecautionsofuse.

References:

1.J.G.M.Derksen,G.M.vanEijnatten,JLahr,P.vanderLindeandA.G.M.Kroon-EnviromentalEffectsofHumanPharmaceuticals,p225,RIWAReport2000.051,Leleystad,TheNetherlands
2.ElineP.Meulenberg,GijsbertO.H.Peelen,EddieLukkienandKeesKoopal–Immunochemicaldetectionmethodsforbioactivepollutants–Intern.J.Environ.Anal.Chem.Vol.85,No.12-13,15October-15November2005,861-870

Caution:

ThisproductisintendedFORRESEARCHUSEONLY,andFORTESTSINVITRO,notforuseindiagnosticortherapeuticproceduresinvolvinghumansoranimals.Thisproductcontainssodiumazide.Topreventformationoftoxicvapors,donotmixwithstrongacidicsolutions.Topreventformationofpotentiallyexplosivemetallicazidesinmetalplumbing,alwayswashintodrainwithcopiousquantitiesofwater.Thisdatasheetisasaccurateasreasonablyachievable,butNordic-Mubioacceptsnoliabilityforanyinaccuraciesoromissionsinthisinformation.

Noridic-Mubio是荷兰的一家著名的免疫学试剂生产厂商，因收购An Der Grub Bio Research GmbH(ADG)，增加了自己的产品线：全球最好的固定破膜剂FIX&PERM 。Nordic-Mubio严格遵照ISO9001标准生产高质量的抗体，主要为针对细胞粘附蛋白、核蛋白和骨架蛋白的抗体。同时Nordic-Mubio也是斑马鱼抗体开发的引领者之一，拥有50多种可用于斑马鱼免疫荧光检测的抗体。