Background:

Ibuprofenisananti-inflammatorydrugusedforpainrelief,feverreductionandagainstswelling.Itisoneofthemostsoldover-the-counterdrugs.Itisfoundintheenvironment,especiallyinthewaterenvironmentintheneighbourhoodoflargecitiesandhospitals.

Source:

Rabbitimmuneserum

Product:

Eachvialcontains0.1ml10mg/mlserum

Applications:

Dilutionof1/7,000fromthedeliveredimmuneserum.(Thetiterisdefinedasthedilutionthatgives50%oftheabsorbancefromthemaximumabsorbancewhentestedwithELISA).SuggestedconcentrationtouseinELISA:1/5,000fromthedeliveredsolution.Platesarecoatedwith400ng/mlOVA-derivative.HRP-conjugatedanti-rabbitIgGasatracer1/8,000

CrossReactivity:

Compoundtested%Cross-reactivityBezafibrate0.4%Gemfibrozil0.2%BisphenolA0.6%Ibuprofen100%Carazolol<0.1% Metoprolol 0.1% Chlorpyrifos 0.3% Naproxen 2.2% Clofibrinic acid 0.3% Nonylphenol 1.3% Diclofenac <0.1% Octylphenol 0.6% Erythromycine 0.1% Propanolol 0.1% Fenitrothion 0.5% Vinclozolin <0.1% Fenofibrate 0.5% Zearalenon 0.2%

Specificity:Immunogen:BSA-Ibuprofenderivativeconjugate,Target:Ibuprofen,CASno.:15687-27-1,Solubility:Organicsolvents,PEGs.

Storage:

Storeat4°Coraliquotandstoreat-20°Cforlongerperiods.Precautionsshouldbetakenuponstorageforlongerperiods.ProblemsoflongtermstABIlitymayoccurwithhighlydilutedsolutions.Nootherpreservativeagenthasbeenaddedtothepresentformulation.Forlongstoragepurposesinsolutiontheadditionofsodiumazideat0.02%isadvisedwiththeappropriateprecautionsofuse.

References:

1.J.G.M.Derksen,G.M.vanEijnatten,JLahr,P.vanderLindeandA.G.M.Kroon-EnviromentalEffectsofHumanPharmaceuticals,p225,RIWAReport2000.051,Leleystad,TheNetherlands
2.ElineP.Meulenberg,GijsbertO.H.Peelen,EddieLukkienandKeesKoopal–Immunochemicaldetectionmethodsforbioactivepollutants–Intern.J.Environ.Anal.Chem.Vol.85,No.12-13,15October-15November2005,861-870

Caution:

ThisproductisintendedFORRESEARCHUSEONLY,andFORTESTSINVITRO,notforuseindiagnosticortherapeuticproceduresinvolvinghumansoranimals.Thisproductcontainssodiumazide.Topreventformationoftoxicvapors,donotmixwithstrongacidicsolutions.Topreventformationofpotentiallyexplosivemetallicazidesinmetalplumbing,alwayswashintodrainwithcopiousquantitiesofwater.Thisdatasheetisasaccurateasreasonablyachievable,butNordic-Mubioacceptsnoliabilityforanyinaccuraciesoromissionsinthisinformation.

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