Background:

BisphenolA(BPA)ispredominantlyusedintheproductionofpolycarbonateplasticsandepoxyresinsthatareusedinmanyproducts.Itisreleasedintotheenvironmentandfood.BPAisanendocrinedisruptorwithestrogenicandobesogenicproperties.Itinfluencesreproductionandhasanepigeneticeffectalreadyinthefoetus.

Source:

Rabbitimmuneserum

Product:

Eachvialcontains0.1mlofserum

Applications:

Titeroftheantibodyisabout50,000,whichmeansthatintheELISAadilutionof50,000timeswillgive50%binding.

CrossReactivity:

CrossReactivityinadirectassayMoleculescontainingaphenolicgroup%CrossReactivityBisphenolA100%4,4"-(ethylidene)bisphenol10%Bis-(4-hydroxyphenyl)-methane1%Nonylphenol1%4-cumylphenol20%Moleculeslackingaphenolicgroup%CrossReactivityVinclozolin0.1%Pirimifos-ethyl< 0.1% 17ß-EstrADIol< 0.1% 2,4 D 0.1% Sulfadimidine < 0.1% Cross Reactivity in an indirect assay Molecules containing a phenolic group % Cross Reactivity Bisphenol A 100% 4,4"-(ethylidene) bisphenol 100% Bis-(4-hydroxyphenyl)-methane 1 % 4-cumylphenol 100% Molecules lacking a phenolic group % Cross Reactivity Vinclozolin < 0.1% Pirimifos-ethyl < 0.1% 2,4 D 0.1% Fenitrothion < 0.1% Chlorpyrifos-methyl < 0.1% Erythromycine < 0.1%

Specificity:

Immunogen:BSA-BisphenolValericAcid(BVA),Target:BisphenolA,CASno.:80-05-7,Solubility:Acetone,Ethanol,Ether,Benzene.

Storage:

Storeat4°Coraliquotandstoreat-20°Cforlongerperiods.Precautionsshouldbetakenuponstorageforlongerperiods.ProblemsoflongtermstABIlitymayoccurwithhighlydilutedsolutions.Nootherpreservativeagenthasbeenaddedtothepresentformulation.Forlongstoragepurposesinsolutiontheadditionofsodiumazideat0.02%isadvisedwiththeappropriateprecautionsofuse.

References:

1.ElineP.Meulenberg,KeesKoopalandRiaRhemrev-Immunoassaysforalkylphenolicpollutantswithendocrinedisruptingactivity.Intern.J.Environ.Anal.Chem.Vol85,no12-13,15October-15November2005,871-883

Caution:

ThisproductisintendedFORRESEARCHUSEONLY,andFORTESTSINVITRO,notforuseindiagnosticortherapeuticproceduresinvolvinghumansoranimals.Thisproductcontainssodiumazide.Topreventformationoftoxicvapors,donotmixwithstrongacidicsolutions.Topreventformationofpotentiallyexplosivemetallicazidesinmetalplumbing,alwayswashintodrainwithcopiousquantitiesofwater.Thisdatasheetisasaccurateasreasonablyachievable,butNordic-Mubioacceptsnoliabilityforanyinaccuraciesoromissionsinthisinformation.

Noridic-Mubio是荷兰的一家著名的免疫学试剂生产厂商，因收购An Der Grub Bio Research GmbH(ADG)，增加了自己的产品线：全球最好的固定破膜剂FIX&PERM 。Nordic-Mubio严格遵照ISO9001标准生产高质量的抗体，主要为针对细胞粘附蛋白、核蛋白和骨架蛋白的抗体。同时Nordic-Mubio也是斑马鱼抗体开发的引领者之一，拥有50多种可用于斑马鱼免疫荧光检测的抗体。