Background:

Carcinoembryonicantigen(CEA)isanoncofetalantigen,whichisexpressedbythefetus,repressedduringnormaladultlifeandderepressedinvarioustumours.NormallyCEAoccursinfetalcolon,liverandpancreas.Inadult,CEAisfoundincolorectalcancer,incarcinomasoftheintestine,andintumoursofthepancreas,lungandthyroid.

Source:

Polyclonalanti-CEAwasobtainedbyimmunizingarabbitwithhumanCEA.

Product:

Eachvialcontains250µlrabbitpolyclonalantiserumcontaining0.09%sodiumazide.

Applications:

Polyclonalanti-CEAissuitableforimmunohistochemistryonfrozenandparaffin-embeddedtissues.Optimalantibodydilutionshouldbedeterminedbytitration;recommendedrangeis1:1500–1:5000usingPAP,or1:1000–1:2000usingFITCwithovernightincubationat+4°C.

Specificity:

Absorptionwith10-100mgimmunogenpermldilutedantiserumabolishesthestaining.

Storage:

Storeat4°C,orinsmallaliquotsat-20°C.

References:

Noreferencesavailable.

Caution:

ThisproductisintendedFORRESEARCHUSEONLYandFORTESTSINVITRO,notforuseindiagnosticortherapeuticproceduresinvolvinghumansoranimals.Thisproductcontainssodiumazide.Topreventformationoftoxicvapors,donotmixwithstrongacidicsolutions.Topreventformationofpotentiallyexplosivemetallicazidesinmetalplumbing,alwayswashintodrainwithcopiousquantitiesofwater.Thisdatasheetisasaccurateasreasonablyachievable,butNordic-MubioBVacceptsnoIiABIlityforanyinaccuraciesoromissionsinthisinformation.

Noridic-Mubio是荷兰的一家著名的免疫学试剂生产厂商，因收购An Der Grub Bio Research GmbH(ADG)，增加了自己的产品线：全球最好的固定破膜剂FIX&PERM 。Nordic-Mubio严格遵照ISO9001标准生产高质量的抗体，主要为针对细胞粘附蛋白、核蛋白和骨架蛋白的抗体。同时Nordic-Mubio也是斑马鱼抗体开发的引领者之一，拥有50多种可用于斑马鱼免疫荧光检测的抗体。